Drew Barrymore and Cameron Diaz have known each other for over thirty years, having met when they were fourteen and sixteen, respectively.
MORE: Drew Barrymore admits to difficulties with revealing childhood trauma
They have starred in movies together, partied together, seen one another's ups and downs, plus, have witnessed a slew of different significant others each has dated.
You're not always going to like the person your best friend is dating, and during a recent conversation on The Drew Barrymore Show, Cameron opened up about how she really feels about the host's dating life.
WATCH: Cameron Diaz shows a glimpse of her new kitchen at home
MORE: Drew Barrymore celebrates her daughter's birthday with an adorable photo you can't miss
During a conversation that took place as they were being driven around New York City, Drew proposed they play a game in which whenever they stopped at a red light, Cameron had to make a confession.
Leaving the juiciest for last, she finally asked the There's Something About Mary lead: "Did you ever lie about liking anyone that I have dated?"
The two quickly were engulfed in hysterical laughter, and the mother-of-two first answered for her longtime friend, saying: "You're incapable of doing that. It's truth or nothing with you."
The two were honest about their friendship
Cameron agreed, admitting: "I could take a hard stance on things," though she added: "But hey, I can be persuaded if it's like… if he can give me a good argument."
MORE: Drew Barrymore steps out with Jimmy Fallon and Gayle King for celebratory night
MORE: Drew Barrymore admits her on-set personality is very 'unlike' her
She maintained: "I would never lie about somebody that you were dating, and say that I liked them if I didn't."
Drew in fact was briefly married to her and Cameron's co-star from Charlie's Angels, Tom Green
Drew proved that she was certainly telling the truth now too, insisting: "I know how you feel about everyone that I've dated."
Fans couldn't help but gush over seeing their long lasting off-screen bond, taking to social media to write: "It's so nice that they're truly close as their Charlie's Angels counterparts," and: "Love when you and Cameron get together," as well as: "I love both of these ladies so much! I really want to see them do a movie together again. That would be awesome!" plus another fan added: "My soul is healed. I love Drew and I love Cameron!
Read more HELLO! US stories here
Like this story? Sign up to our newsletter to get other stories like this delivered straight to your inbox.