Though Angelina Jolie has led a largely private life in recent years, and save for her work as an actress, and some red carpet appearances, she keeps sharing details about her personal life to a minimum, she has never stopped being vocal about the things she truly cares about.
She has been happy to publicly support her children's career ventures, most recently working on The Outsiders musical with her daughter Vivienne, and has continued to be outspoken about the various humanitarian causes she supports.
The Maleficent actress has also been transparent about her health, its ups and downs, and certain preventative measures she has taken to maintain it.
Read on for a look back at her health journey.
She had a double mastectomy
In 2013, six years after her mother Marcheline Bertrand passed away aged 56 after a battle with both breast and ovarian cancer, Angelina decided to undergo a preventative double mastectomy, when she was 37 years old.
In an op-ed in the New York Times once the months-long procedure was completed, she revealed that she came to the decision after learning that she carried the BRCA1 gene, which, according to the National Library of Medicine, means she had "an 87% risk of developing breast cancer during her lifetime."
After the process, which she said narrowed her risks of developing breast cancer to 5%, she wrote: "I am writing about it now because I hope that other women can benefit from my experience. Cancer is still a word that strikes fear into people's hearts, producing a deep sense of powerlessness. But today it is possible to find out through a blood test whether you are highly susceptible to breast and ovarian cancer, and then take action."
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She shared that she was motivated to take action with her six children, Maddox, 22, Pax, 20, Zahara, 19, Shiloh, 18, and twins Vivienne and Knox, who just turned 16, in mind, noting: "I can tell my children that they don't need to fear they will lose me to breast cancer."
She added: "They know that I love them and will do anything to be with them as long as I can," and maintained: "On a personal note, I do not feel any less of a woman. I feel empowered that I made a strong choice that in no way diminishes my femininity."
She developed Bell's palsy amid her divorce from Brad Pitt
Though in her inspiring story about the double mastectomy, Angelina spoke fondly about her ex Brad Pitt's support through the process, just three years later, in September 2016, the once beloved couple announced their plans to divorce. Their split came two years after their wedding — they started dating in 2005 — and in their subsequent (and ongoing) legal battle, court documents allege Brad was physically and emotionally abusive towards Angelina and some of their kids while traveling via private plane that same month.
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Late last year, speaking with WSJ. Magazine about her return to the screen with Pablo Larraín's Maria Callas biopic, and her new fashion venture Atelier Jolie, Angelina opened up about the changes in her body she felt before and in the midst of her divorce from Brad.
"My body reacts very strongly to stress," she said, before revealing: "My blood sugar goes up and down. I suddenly had Bell's palsy six months before my divorce."
Bell's palsy is a rare, unexplained episode of facial muscle weakness or paralysis, and it typically resolves on its own within six months.