Amanda Knox could be seen crying as she lost her bid to overturn a slander conviction in Italy, 17 years after she was initially accused of the murder of her flatmate, 21-year-old Meredith Kercher.
The American woman was eventually cleared of the murder in 2015, and released from prison four years after her initial conviction in 2011 - but she still faced a slander ruling for wrongly accusing her employer of the murder during an interrogation.
Here is everything you need to know, as Amanda Knox has been re-convicted for slander.
Why was Amanda accused of defamation?
Amanda was convicted of the defamation of her former employer, Patrick Lumumba in 2009. She was sentenced to three years in prison, which was deemed served by the time she was formally convicted, as she had been in prison awaiting her murder trial.
Amanda had worked part-time for the bar owner - and during a 2007 interrogation, she accused him of the murder, which led to his arrest and two-week incarceration.
The then-20-year-old signed two statements about the accusation prepared by police, but later cast doubt on her accusation with a handwritten note, which led to her conviction of slander.
The court ruling in the retrial
The 36-year-old appealed this final conviction, after being exonerated in 2015, and acquitted for a different defamation charge where she claimed to have been struck by policewomen during her interrogation.
The Italian court, including two judges, a six-jury panel and two alternates, upheld the decision that she was guilty of slander.
During the emotional trial, the 36-year-old mother-of-two apologized to the court for not trying harder to retract the accusation against Mr Lumumba. She said that she was a young person in an existential crisis when she accused him: "I did not know who the assassin was."
Amanda filed her appeal on the basis that the European Court of Human Rights had ruled that the Italian police had violated her rights during interrogations, as she was not provided with a lawyer or an interpreter. Her appeal claimed that her accusations against her former boss were made during these interviews, in which it was claimed she had also implicated herself.
Will Amanda go back to prison?
She will not serve any more jail time, as the sentence counts as time she already served in prison.
The murder of Meredith Kercher
Amanda was accused of the murder of her flatmate Meredith in 2007, who was found dead in her locked bedroom by police in their shared apartment. The 21-year-old English woman's throat had been cut and she had been sexually assaulted.
Amanda, her then-boyfriend Raffaele Sollecito, and a third person called Rudy Guede were convicted of murder and sexual violence and imprisoned. The case attracted global attention.
The murder convictions for Amanda and Raffaele were overturned in 2011, due to an independent review of key forensic evidence, but that acquittal was then overturned by Italy's supreme court in 2013 and they were convicted again in 2014. By this point, Amanda was back in the US and didn't attend this trial.
It was only in 2015 that Amanda and Raffaele were definitively exonerated of the murder by Italy's highest court, who voided the 2013 re-conviction.
Where is Amanda now?
The 36-year-old is married to author Christopher Robinson and has two children. She wrote the memoir Waiting to Be Heard in 2013.